home
Our facilities
Physicians & Staff
Infertility
Male Infertility
Programs
Success Rates
Ovulation Calculator
Fees
Faq
Forms
Announcements
Glossary
Contact Us
Links
Site Map
 
 
 
 

ISIS Regional Fertility Centre

2180 Meadowvale Blvd.
Mississauga
Ontario L5N 5S3
Tel: 905-816-9822
Fax: 905-816-9833


Contact Us

 
In Vitro Maturation (IVM)
« Back
IVM was originally developed as an alternative to standard IVF protocols. It is not routinely available at most IVF clinics. This program is under development at ISIS. IVM has several advantages over conventional IVF. Benefits of IVM include simple and less time-consuming protocols, no or minimal use of fertility drugs, and reduced cost of treatment. The inherent risk of ovarian hyperstimulation that can occur during ovulation induction is entirely avoided. Women that choose to use IVM most commonly are those who have experienced excessive ovarian hyperstimulation in the past or who wish not to use ovulation induction medications.

The majority of use of IVM worldwide has been in

women with polycystic ovarian syndrome. Far fewer cycles have been carried out with women with regular menstrual cycles. This has mainly been because the low number of eggs retrieved and thus fewer embryos resulting for transfer have been thought to reduce the applicability of IVM in this group of patients. Approximately 400 babies have been born worldwide as a result of IVM. Data is limited regarding the safety of IVM with respect to the children born from this technology, though it appears reassuring.

With IVM, immature eggs are retrieved from the unstimulated ovaries and then are cultured in specific media to promote maturation. Success rates published in the literature show that pregnancy rates may be as high as 23% in experienced laboratories when performed in young healthy women.

Success rates have been shown to be higher with the addition of some ovarian stimulating medications. It is not clear yet what features of patients will predict a good prognosis of success with this treatment.
Home | Programs | Success Rates | Fees | Physicians | Glossary | Events | FAQ | Contact | Link | Site Map

Copyright © 2008 ISIS Regional Fertility Centre. All Rights Reserved.


Our fertility specialists helped many patients from Kitchener, Guelph, Hamilton, Burlington, Mississauga, Oakville, Milton, Brampton, Toronto, and throughout Ontario.